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Alterations in intestinal permeability

Intestinal permeability – a new target for disease prevention and therapy

Intestinal Barrier Function: Molecular Regulation and Disease Pathogenesis

Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease

Intestinal Permeability

Intestinal Barrier Function: Molecular Regulation and Disease Pathogenesis

Intestinal permeability parameters in obese patients are correlated with metabolic syndrome risk factors


Role of Glutamine in Protection of Intestinal Epithelial Tight Junctions

Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study.

Possible Links between Intestinal Permeability and Food Processing: A Potential Therapeutic Niche for Glutamine

Glutamine: A novel approach to chemotherapy-induced toxicity

Molecular Mechanisms Contributing to Glutamine-Mediated Intestinal Cell Survival

Glutamine protects against apoptosis via downregulation of Sp3 in intestinal epithelial cells

Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome.

Glutamine and whey protein improve intestinal permeability and morphology in patients with Crohn's disease: a randomized controlled trial.

Molecular Mechanisms Contributing to Glutamine-Mediated Intestinal Cell Survival

Glutamine protects against apoptosis via downregulation of Sp3 in intestinal epithelial cells

Effect of a glutamine-supplemented enteral diet on methotrexate-induced enterocolitis.

Clinical Use of Glutamine Supplementation

Glutamine Deprivation Alters Intestinal Tight Junctions via a PI3-K/Akt Mediated Pathway in Caco-2 Cells

Inflammation rather than nutritional depletion determines glutamine concentrations and intestinal permeability.

Importance of nutrition in inflammatory bowel disease


Gut permeability, intestinal morphology, and nutritional depletion.

The Roles of Glutamine in the Intestine and Its Implication in Intestinal Diseases

Molecular Mechanisms Contributing to Glutamine-Mediated Intestinal Cell Survival

Effect of glutamine on change in early postoperative intestinal permeability and its relation to systemic inflammatory response.






Quercetin Enhances Intestinal Barrier Function through the Assembly of Zonnula Occludens-2, Occludin, and Claudin-1 and the Expression of Claudin-4 in Caco-2 Cells

Role of flavonoids in intestinal tight junction regulation

The role of quercetin, flavonols and flavones in modulating inflammatory cell function.


Flavonoids and heart health: proceedings of the ILSI North America Flavonoids Workshop, May 31-June 1, 2005, Washington, DC.

Quercetin reduces inflammatory pain: inhibition of oxidative stress and cytokine production.

Nutritional Protocol for the Treatment of Intestinal Permeability Defects and Related Conditions

Quercetin as a potential anti-allergic drug: which perspectives?

Mucosal mast cells: Effect of quercetin and other flavonoids on antigen-induced histamine secretion from rat intestinal mast cells

Mucosal mast cells. III. Effect of quercetin and other flavonoids on antigen-induced histamine secretion from rat intestinal mast cells.


Flavonoids in vegetable foods commonly consumed in Brazil and estimated ingestion by the Brazilian population.




Foods With the Highest Content of Quercetin



Effect of licorice on the reduction of body fat mass in healthy subjects

The Effect of Dried Glycyrrhiza Glabra L. Extract on Obesity Management with Regard to PPAR-γ2 (Pro12Ala) Gene Polymorphism in Obese Subjects Following an Energy Restricted Diet

Aqueous extracts and polysaccharides from Marshmallow roots (Althea officinalis L.): Cellular internalisation and stimulation of cell physiology of human epithelial cells in vitro

Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon


An Evaluation of Root Phytochemicals Derived from Althea officinalis (Marshmallow) and Astragalus membranaceus as Potential Natural Components of UV Protecting Dermatological Formulations.

Combination of herbal extracts and platelet-rich plasma induced dermal papilla cell proliferation: involvement of ERK and Akt pathways.

Protective effects of ginger and marshmallow extracts on indomethacin-induced peptic ulcer in rats

Glycyrrhiza glabra: Medicine over the millennium

Glycyrrhiza glabra - a plant for the future


Could Licorice Help You Get Lean?



N-Acetylglucosamine: Production and Applications


What is gluten?

Celiac Disease

Effect of Gliadin on Permeability of Intestinal Biopsy Explants from Celiac Disease Patients and Patients with Non-Celiac Gluten Sensitivity

Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3

Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines.

Allergy and the gastrointestinal system

The Gut: Where Bacteria and Immune System Meet

Your gut is the cornerstone of your immune system

Role of Kamut® brand khorasan wheat in the counteraction of non-celiac wheat sensitivity and oxidative damage

A khorasan wheat-based replacement diet improves risk profile of patients with type 2 diabetes mellitus (T2DM): a randomized crossover trial

Characterization of Khorasan wheat (Kamut) and impact of a replacement diet on cardiovascular risk factors: cross-over dietary intervention study

Effect of Triticum turgidum subsp. turanicum wheat on irritable bowel syndrome: a double-blinded randomised dietary intervention trial

Do ancient types of wheat have health benefits compared with modern bread wheat?


Role of non-steroidal anti-inflammatory drugs on intestinal permeability and nonalcoholic fatty liver disease

Intestinal permeability and inflammation inpatients on NSAIDs

Mortality with upper gastrointestinal bleeding and perforation: effects of time and NSAID use

Number needed to kill. Individual drug risk with NSAIDs.

Total OTC drug retail sales in the U.S. from 1965 to 2017 (in billion U.S. dollars)



Pharmacology of Proton Pump Inhibitors

Proton Pump Inhibitors (PPIs) Side Effects, LIst of Names, and Uses

The innovative potential of Lactobacillus rhamnosus LR06, Lactobacillus pentosus LPS01, Lactobacillus plantarum LP01, and Lactobacillus delbrueckii Subsp. delbrueckii LDD01 to restore the "gastric barrier effect" in patients chronically treated with PPI: a pilot study.

How Diet, Exercise, and Probiotics Influence Diversity in Gut Microbiota

The influence of long-term use of proton pump inhibitors on the gut microbiota: an age-sex-matched case-control study

Correlation between chronic treatment with proton pump inhibitors and bacterial overgrowth in the stomach: any possible beneficial role for selected lactobacilli?

Is It Useful to Administer Probiotics Together With Proton Pump Inhibitors in Children With Gastroesophageal Reflux?

Proton pump inhibitors affect the gut microbiome

Long-term Use of PPIs Has Consequences for Gut Microbiome

The Gastric and Intestinal Microbiome: Role of Proton Pump Inhibitors.

Long-term treatment with proton pump inhibitors is associated with undesired weight gain


5 Things You Should Know About Stress

Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options

Corticotropin-releasing factor receptors and stress-related alterations of gut motor function

CRF induces intestinal epithelial barrier injury via the release of mast cell proteases and TNF-α.

Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders

Neonatal maternal separation predisposes adult rats to colonic barrier dysfunction in response to mild stress.

Exposure to a Social Stressor Alters the Structure of theIntestinal Microbiota: Implications for Stressor-InducedImmunomodulation


Vagus Nerve as Modulator of the Brain-Gut Axis in Psychiatric and Inflammatory Disorders.

The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis.

[Brain-gut axis dysfunction].

Principles and clinical implications of the brain–gut–enteric microbiota axis

Role of the brain-gut axis in the pathophysiology of Crohn's disease.

The Human Brain in Numbers: A Linearly Scaled-up Primate Brain

Gut feelings: the emerging biology of gut–brain communication

Acne vulgaris, probiotics and the gut-brain-skin axis - back to the future?

The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems

Gut/brain axis and the microbiota

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour.

Gut-brain axis: how the microbiome influences anxiety and depression.

Correlation between the human fecal microbiota and depression.

Altered brain-gut axis in autism: comorbidity or causative mechanisms?

The microbiota–gut–brain axis in gastrointestinal disorders: stressed bugs, stressed brain or both?

The Gut-Brain Connection: How it Works and The Role of Nutrition

Think Twice: How the Gut's "Second Brain" Influences Mood and Well-Being



Enteric nervous system, serotonin, and the irritable bowel syndrome.

Serotonergic Mechanisms Regulating the GI Tract: Experimental Evidence and Therapeutic Relevance

Enteric nervous system development: Recent progress and future challenges.

A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I. Affective disorders.

Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis

Influence of Tryptophan and Serotonin on Mood and Cognition with a Possible Role of the Gut-Brain Axis

Neurotransmitters: The critical modulators regulating gut-brain axis

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis.

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

Gut bacteria help regulate serotonin levels

Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan.

The Expanded Biology of Serotonin

Serotonin: The Happy Hormone Produced In Our Gut



Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease

Intestinal Permeability and its Regulation by Zonulin: Diagnostic and Therapeutic Implications

Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer


Dysbiosis of the gut microbiota in disease

Stressor Exposure Disrupts Commensal Microbial Populations in the Intestines and Leads to Increased Colonization by Citrobacter rodentium

Exposure to a Social Stressor Alters the Structure of the Intestinal Microbiota: Implications for Stressor-Induced Immunomodulation

Role of the gut microbiota in nutrition and health