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INTESTINAL PERMEABILITY:

Alterations in intestinal permeability

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1856434/

Intestinal permeability – a new target for disease prevention and therapy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253991/

Intestinal Barrier Function: Molecular Regulation and Disease Pathogenesis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266989/

Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease

https://www.sciencedirect.com/science/article/pii/S1568997215000245

Intestinal Permeability

https://www.sciencedirect.com/topics/medicine-and-dentistry/intestinal-permeability

Intestinal Barrier Function: Molecular Regulation and Disease Pathogenesis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266989/

Intestinal permeability parameters in obese patients are correlated with metabolic syndrome risk factors

https://www.clinicalnutritionjournal.com/article/S0261-5614(12)00038-6/abstract

L-GLUTAMINE:

Role of Glutamine in Protection of Intestinal Epithelial Tight Junctions

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369670/

Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study.

https://www.ncbi.nlm.nih.gov/pubmed/25226827

https://www.nature.com/articles/ejcn2014184.pdf

Possible Links between Intestinal Permeability and Food Processing: A Potential Therapeutic Niche for Glutamine

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898551/

Glutamine: A novel approach to chemotherapy-induced toxicity

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385273/

Molecular Mechanisms Contributing to Glutamine-Mediated Intestinal Cell Survival

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432018/

Glutamine protects against apoptosis via downregulation of Sp3 in intestinal epithelial cells

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006244/

Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome.

https://www.ncbi.nlm.nih.gov/pubmed/30108163?dopt=Abstract

Glutamine and whey protein improve intestinal permeability and morphology in patients with Crohn's disease: a randomized controlled trial.

https://www.ncbi.nlm.nih.gov/pubmed/22038507

Molecular Mechanisms Contributing to Glutamine-Mediated Intestinal Cell Survival

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432018/

Glutamine protects against apoptosis via downregulation of Sp3 in intestinal epithelial cells

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006244/

Effect of a glutamine-supplemented enteral diet on methotrexate-induced enterocolitis.

https://www.ncbi.nlm.nih.gov/pubmed/3138440

Clinical Use of Glutamine Supplementation

https://academic.oup.com/jn/article/138/10/2040S/4670117

Glutamine Deprivation Alters Intestinal Tight Junctions via a PI3-K/Akt Mediated Pathway in Caco-2 Cells

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666365/

Inflammation rather than nutritional depletion determines glutamine concentrations and intestinal permeability.

https://www.ncbi.nlm.nih.gov/pubmed/15380915

Importance of nutrition in inflammatory bowel disease

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678578/

       

Gut permeability, intestinal morphology, and nutritional depletion.

https://www.ncbi.nlm.nih.gov/pubmed/9437674

The Roles of Glutamine in the Intestine and Its Implication in Intestinal Diseases

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454963/

Molecular Mechanisms Contributing to Glutamine-Mediated Intestinal Cell Survival

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432018/

Effect of glutamine on change in early postoperative intestinal permeability and its relation to systemic inflammatory response.

https://www.ncbi.nlm.nih.gov/pubmed/15222054

 

Glutamine

https://www.ncbi.nlm.nih.gov/pubmed/11193715

Glutamine

https://examine.com/supplements/glutamine/

 

QUERCETIN:

Quercetin Enhances Intestinal Barrier Function through the Assembly of Zonnula Occludens-2, Occludin, and Claudin-1 and the Expression of Claudin-4 in Caco-2 Cells

https://academic.oup.com/jn/article/139/5/965/4670389

Role of flavonoids in intestinal tight junction regulation

https://www.sciencedirect.com/science/article/pii/S0955286310001877

The role of quercetin, flavonols and flavones in modulating inflammatory cell function.

https://www.ncbi.nlm.nih.gov/pubmed/20887269

 

Flavonoids and heart health: proceedings of the ILSI North America Flavonoids Workshop, May 31-June 1, 2005, Washington, DC.

https://www.ncbi.nlm.nih.gov/pubmed/17311968

Quercetin reduces inflammatory pain: inhibition of oxidative stress and cytokine production.

https://www.ncbi.nlm.nih.gov/pubmed/19899776

Nutritional Protocol for the Treatment of Intestinal Permeability Defects and Related Conditions

https://www.naturalmedicinejournal.com/journal/2010-03/nutritional-protocol-treatment-intestinal-permeability-defects-and-related

Quercetin as a potential anti-allergic drug: which perspectives?

https://www.ncbi.nlm.nih.gov/pubmed/21625024

Mucosal mast cells: Effect of quercetin and other flavonoids on antigen-induced histamine secretion from rat intestinal mast cells

https://www.jacionline.org/article/0091-6749(84)90453-6/pdf

Mucosal mast cells. III. Effect of quercetin and other flavonoids on antigen-induced histamine secretion from rat intestinal mast cells.

https://www.ncbi.nlm.nih.gov/pubmed/6202731

 

Flavonoids in vegetable foods commonly consumed in Brazil and estimated ingestion by the Brazilian population.

https://www.ncbi.nlm.nih.gov/pubmed/14995109

 

Quercetin

https://pubchem.ncbi.nlm.nih.gov/compound/quercetin#section=Top

Quercetin

https://www.webmd.com/vitamins/ai/ingredientmono-294/quercetin

Foods With the Highest Content of Quercetin

https://www.livestrong.com/article/301326-foods-with-the-highest-content-of-quercetin/

Quercetin

https://examine.com/supplements/quercetin/

SWEET ROOT EXTRACTS:

Effect of licorice on the reduction of body fat mass in healthy subjects

https://www.researchgate.net/publication/5378458_Effect_of_licorice_on_the_reduction_of_body_fat_mass_in_healthy_subjects

The Effect of Dried Glycyrrhiza Glabra L. Extract on Obesity Management with Regard to PPAR-γ2 (Pro12Ala) Gene Polymorphism in Obese Subjects Following an Energy Restricted Diet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527236/

Aqueous extracts and polysaccharides from Marshmallow roots (Althea officinalis L.): Cellular internalisation and stimulation of cell physiology of human epithelial cells in vitro

https://www.sciencedirect.com/science/article/pii/S0378874109006102?via=ihub

https://www.ncbi.nlm.nih.gov/pubmed/19799989

Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon

https://www.tandfonline.com/doi/abs/10.3109/13880209.2010.516754

 

An Evaluation of Root Phytochemicals Derived from Althea officinalis (Marshmallow) and Astragalus membranaceus as Potential Natural Components of UV Protecting Dermatological Formulations.

https://www.ncbi.nlm.nih.gov/pubmed/26953144

Combination of herbal extracts and platelet-rich plasma induced dermal papilla cell proliferation: involvement of ERK and Akt pathways.

https://www.ncbi.nlm.nih.gov/pubmed/?term=marshmallow+hair

Protective effects of ginger and marshmallow extracts on indomethacin-induced peptic ulcer in rats

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518423/

Glycyrrhiza glabra: Medicine over the millennium

http://nopr.niscair.res.in/bitstream/123456789/8122/1/NPR%204%285%29%20358-367.pdf

Glycyrrhiza glabra - a plant for the future

http://mjpms.in/index.php/mjpms/article/view/126

 

Could Licorice Help You Get Lean?

https://www.webmd.com/diet/news/20000714/licorice-can-reduce-body-fat#1

 

N-ACETYL-GLUCOSAMINE:

N-Acetylglucosamine: Production and Applications

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953398/

GLUTEN:

What is gluten?

https://onlinelibrary.wiley.com/doi/full/10.1111/jgh.13703

Celiac Disease

https://www.mayoclinic.org/diseases-conditions/celiac-disease/symptoms-causes/syc-20352220

Effect of Gliadin on Permeability of Intestinal Biopsy Explants from Celiac Disease Patients and Patients with Non-Celiac Gluten Sensitivity

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377866/

Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653457/

Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines.

https://www.ncbi.nlm.nih.gov/pubmed/16635908

Allergy and the gastrointestinal system

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515351/

The Gut: Where Bacteria and Immune System Meet

https://www.hopkinsmedicine.org/research/advancements-in-research/fundamentals/in-depth/the-gut-where-bacteria-and-immune-system-meet

Your gut is the cornerstone of your immune system

https://www.health24.com/Medical/Flu/Preventing-flu/your-gut-is-the-cornerstone-of-your-immune-system-20160318

Role of Kamut® brand khorasan wheat in the counteraction of non-celiac wheat sensitivity and oxidative damage

https://www.sciencedirect.com/science/article/pii/S0963996914000829

A khorasan wheat-based replacement diet improves risk profile of patients with type 2 diabetes mellitus (T2DM): a randomized crossover trial

https://link.springer.com/article/10.1007/s00394-016-1168-2

Characterization of Khorasan wheat (Kamut) and impact of a replacement diet on cardiovascular risk factors: cross-over dietary intervention study

https://www.nature.com/articles/ejcn2012206

Effect of Triticum turgidum subsp. turanicum wheat on irritable bowel syndrome: a double-blinded randomised dietary intervention trial

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405706/

Do ancient types of wheat have health benefits compared with modern bread wheat?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824670/

NSAIDs:

Role of non-steroidal anti-inflammatory drugs on intestinal permeability and nonalcoholic fatty liver disease

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473116/

Intestinal permeability and inflammation inpatients on NSAIDs

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1727292/pdf/v043p00506.pdf

Mortality with upper gastrointestinal bleeding and perforation: effects of time and NSAID use

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698873/

Number needed to kill. Individual drug risk with NSAIDs.

https://www.ncbi.nlm.nih.gov/pubmed/11584724

Total OTC drug retail sales in the U.S. from 1965 to 2017 (in billion U.S. dollars)

https://www.statista.com/statistics/307237/otc-sales-in-theus/

 

PPIS:

Pharmacology of Proton Pump Inhibitors

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855237/

Proton Pump Inhibitors (PPIs) Side Effects, LIst of Names, and Uses

https://www.medicinenet.com/proton-pump_inhibitors/article.htm

The innovative potential of Lactobacillus rhamnosus LR06, Lactobacillus pentosus LPS01, Lactobacillus plantarum LP01, and Lactobacillus delbrueckii Subsp. delbrueckii LDD01 to restore the "gastric barrier effect" in patients chronically treated with PPI: a pilot study.

https://www.ncbi.nlm.nih.gov/pubmed/22955351

How Diet, Exercise, and Probiotics Influence Diversity in Gut Microbiota

https://pdfs.semanticscholar.org/9243/088e1743b4e2bd92c0d527d813df15795f78.pdf

The influence of long-term use of proton pump inhibitors on the gut microbiota: an age-sex-matched case-control study

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773837/

Correlation between chronic treatment with proton pump inhibitors and bacterial overgrowth in the stomach: any possible beneficial role for selected lactobacilli?

https://www.ncbi.nlm.nih.gov/pubmed/25291126

Is It Useful to Administer Probiotics Together With Proton Pump Inhibitors in Children With Gastroesophageal Reflux?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753903/

Proton pump inhibitors affect the gut microbiome

https://gut.bmj.com/content/65/5/740

Long-term Use of PPIs Has Consequences for Gut Microbiome

https://consultqd.clevelandclinic.org/long-term-use-of-ppis-has-consequences-for-gut-microbiome/

The Gastric and Intestinal Microbiome: Role of Proton Pump Inhibitors.

https://www.ncbi.nlm.nih.gov/pubmed/28733944

Long-term treatment with proton pump inhibitors is associated with undesired weight gain

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761557/

STRESS:

5 Things You Should Know About Stress

https://www.nimh.nih.gov/health/publications/stress/index.shtml

Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options

http://www.jpp.krakow.pl/journal/archive/12_11/pdf/591_12_11_article.pdf

Corticotropin-releasing factor receptors and stress-related alterations of gut motor function

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1716215/

CRF induces intestinal epithelial barrier injury via the release of mast cell proteases and TNF-α.

https://www.ncbi.nlm.nih.gov/pubmed/22768175

Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604320/#B204

Neonatal maternal separation predisposes adult rats to colonic barrier dysfunction in response to mild stress.

https://www.ncbi.nlm.nih.gov/pubmed/12388189

Exposure to a Social Stressor Alters the Structure of theIntestinal Microbiota: Implications for Stressor-InducedImmunomodulation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039072/pdf/nihms253984.pdf

VAGUS NERVE (GUT-BRAIN AXIS/SECOND BRAIN):

Vagus Nerve as Modulator of the Brain-Gut Axis in Psychiatric and Inflammatory Disorders.

https://www.ncbi.nlm.nih.gov/pubmed/29593576

The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis.

https://www.ncbi.nlm.nih.gov/pubmed/29467611

[Brain-gut axis dysfunction].

https://www.ncbi.nlm.nih.gov/pubmed/19303539

Principles and clinical implications of the brain–gut–enteric microbiota axis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817714/

Role of the brain-gut axis in the pathophysiology of Crohn's disease.

https://www.ncbi.nlm.nih.gov/pubmed/18431066

The Human Brain in Numbers: A Linearly Scaled-up Primate Brain

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776484/

Gut feelings: the emerging biology of gut–brain communication

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845678/

Acne vulgaris, probiotics and the gut-brain-skin axis - back to the future?

https://gutpathogens.biomedcentral.com/articles/10.1186/1757-4749-3-1

The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367209/

Gut/brain axis and the microbiota

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362231/

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour.

https://www.ncbi.nlm.nih.gov/pubmed/22968153

Gut-brain axis: how the microbiome influences anxiety and depression.

https://www.ncbi.nlm.nih.gov/pubmed/23384445

Correlation between the human fecal microbiota and depression.

https://www.ncbi.nlm.nih.gov/pubmed/24888394

Altered brain-gut axis in autism: comorbidity or causative mechanisms?

https://www.ncbi.nlm.nih.gov/pubmed/25145752

The microbiota–gut–brain axis in gastrointestinal disorders: stressed bugs, stressed brain or both?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214655/

The Gut-Brain Connection: How it Works and The Role of Nutrition

https://www.healthline.com/nutrition/gut-brain-connection

Think Twice: How the Gut's "Second Brain" Influences Mood and Well-Being

https://www.scientificamerican.com/article/gut-second-brain/

 

SEROTONIN:

Enteric nervous system, serotonin, and the irritable bowel syndrome.

https://www.ncbi.nlm.nih.gov/pubmed/17031157

Serotonergic Mechanisms Regulating the GI Tract: Experimental Evidence and Therapeutic Relevance

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526216/

Enteric nervous system development: Recent progress and future challenges.

https://www.ncbi.nlm.nih.gov/pubmed/19783483

A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I. Affective disorders.

https://www.ncbi.nlm.nih.gov/pubmed/12851635

Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393509/

Influence of Tryptophan and Serotonin on Mood and Cognition with a Possible Role of the Gut-Brain Axis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728667/

Neurotransmitters: The critical modulators regulating gut-brain axis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772764/

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis.

https://www.ncbi.nlm.nih.gov/pubmed/25078296

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

https://www.cell.com/cell/fulltext/S0092-8674(15)00248-2

Gut bacteria help regulate serotonin levels

http://www.microbiomeinstitute.org/blog/2015/4/12/gut-bacteria-help-regulate-serotonin-levels

Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan.

https://www.ncbi.nlm.nih.gov/pubmed/2184795

The Expanded Biology of Serotonin

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864293/

Serotonin: The Happy Hormone Produced In Our Gut

https://www.biokplus.com/blog/en_US/gut-health/serotonin-the-happy-hormone-produced-in-our-gut_1

 

ZONULIN:

Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease

https://www.sciencedirect.com/science/article/pii/S0140673600021693?via%3Dihub

Intestinal Permeability and its Regulation by Zonulin: Diagnostic and Therapeutic Implications

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458511/

Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer

https://www.physiology.org/doi/full/10.1152/physrev.00003.2008

DYSBIOSIS:

Dysbiosis of the gut microbiota in disease

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315779/

Stressor Exposure Disrupts Commensal Microbial Populations in the Intestines and Leads to Increased Colonization by Citrobacter rodentium

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849416/?tool=pubmed

Exposure to a Social Stressor Alters the Structure of the Intestinal Microbiota: Implications for Stressor-Induced Immunomodulation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039072/?tool=pubmed

Role of the gut microbiota in nutrition and health

https://www.bmj.com/content/361/bmj.k2179